Ceva Santé Animale
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10 avenue de la Ballastière
33500 Libourne
France
DIRECTOR, BIOTHERAPEUTICS SCIENCES
About us
Ceva Santé Animale (Ceva) is the 5th global animal health company, led by experienced veterinarians, whose mission is to provide innovative health solutions for all animals to ensure the highest level of care and well-being.
With more than 7,000 employees located in 47 countries, Ceva strives daily to bring to life its vision as a One Health company: “Together, beyond animal health”.
2023 turnover: €1.6 billion.
Business offer
Our portfolio includes preventive medicine such as vaccines and animal welfare products, pharmaceuticals and biopharmaceuticals solutions for farm and companion animals, as well as equipment and services to provide the best experience for our customers.
Activities
- Therapeutic Product
- Cardiology
- Infectiology
- Immunology
- Inflammation
- Other
- Target selection & validation
- Expression and pathway analysis of target
- quantification of target
- Hit discovery
- Screening & Identification
- Therapeutic libraries
- In silico
- In-vivo models
- In-vitro & ex-vivo models
- Indication searching
- Immunotherapy lead generation
- Binding & Affinity
- Potency & Specificity
- Epitope mapping
- Pharmacology & Biological activity
- PK/PD bioavailability
- Mode of Action
- Therapeutic efficacy
- Manufacturability
- Production quality
- CMC feasibility
- Immunotherapy lead optimization
- Engineering
- ADC
- Linkers
- Payloads
- Protein scaffolds
- Fragments
- Multi-, bispecific
- Fc-fusion proteins
- Affinity maturation
- Proof of concept
- Pharmacology potency
- Exploratory toxicology
- in-vitro & ex-vivo models
- in-vivo models
- Preclinical biomarkers
- Mechanism/Function
- Mechanism of action
- Safety
- PK/PD features
- Indication Identification
- Drug-Target interaction
- Level of response duration
- Specificity
- Surrogate markers
- Research exploratory Companion biomarkers
- Animal biomarkers
- Predictive biomarkers
- Treatment efficacy
- Risk/benefit profile
- Disease progression / follow-up
- CMC
- GLP compliance
- GLP compliance
- Clinical biomarkers
- Predictive biomarkers
- Treatment efficacy
- Safety
- PK/PD features
- Surrogate markers
- Target Identification
- Expression and pathway analysis of target
- quantification of target
- Gene Delivery System
- Adeno-Associated Virus (AAV)
- Gene Gun
- Electroporation
- Antigen identification, selection, optimization, and validation
- In silico modeling
- Structure-based antigen design
- Reverse vaccinology
- Epidemiology analysis
- Assay development with in-vitro & in-vivo models
- Antigen characterization
- Antigen optimization:
- Generation of mutants
- Antigen selection: pathogen sequencing and functional antigens
- Surface glycoproteins
- Membrane antigens
- Immunogenicity in relevant animal models
- Pathogen-host knowledge
- In-vitro and in-vivo models
- Antigen-protective immune-response profile
- Humoral response characterization:
- Antibody dosage
- Functional antibody assays (neutralization, CDC, ADCC)
- Other serological assays
- Cell mediated immunity response
- T cell assays
- Reactogenicity Assessment
- Research exploratory biomarkers
- protection correlation
- Vaccine: antigen format platforms
- Killed/inactivated virus
- Live attenuated virus
- mRNA vaccine
- Lipid delivery vehicle
- Challenge test – Gold Standard
- In-vivo animal models
- Induced immune response characterization
- CMC
- GLP compliance
- GMP compliance
- Formulation
- Formulation
- Adjuvants
- Lyophilization
- Shipment Monitoring
- Vaccine delivery/Administration routes
- Route of Administration
- Intramuscular route
- intradermal route
- Nasal route
- Mucosal routes
- Other devices: specify
- Delivery/ Encapsulation
- Lipid Nanoparticles
- Nano emulsions
- Adjuvanted delivery systems
- Regulatory safety
- Regulatory safety tests
- Fill & finish
- Lyophilization
- Prefilled syringe
- Vaccine shipment and distribution
- Storage matter
- Cold chain logistics
- Quality control & analytical process monitoring
- Stability Assessment
- Biosafety & Bioanalysis
- Toxicology
- Immune response characterization
- Batch release test
- Potency assay