WhiteLab Genomics
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Contact
4 RUE PIERRE FONTAINE
91000 EVRY-COURCOURONNES
France
Business Development Lead
About us
WhiteLab Genomics is a pioneering startup leveraging Artificial Intelligence to accelerate and mitigate risks in early-stage research and development pipeline for genomic medicine. We are actively engaged in partnerships with renowned academic institutions (Genethon, Brain Institute), as well as small and mid-sized biotech (Flagship Pioneering, SIREN biotech) and pharmaceutical companies (e.g. Sanofi), aimed at addressing critical challenges in the biopharma industry for target discovery, payload, and vector engineering and bioproduction. We are collaborating with Sanofi to develop new gene therapies in ophthalmology (targeting microglia in the CNS) and rare disease.
Business offer
By bringing together the power of computer sciences (e.g. ML, GenAI) and biology, we help our partners to reach their target product profile, faster, in leaner ways. We have developed a proprietary platform including algorithms and databases to improve the design of therapeutic candidates for enhanced safety and efficacy. It includes vectors optimisation such as adeno-associated virus (AAV) and lentivirus, or non-viral like LNP. WLG synergistically combines in-house biomarker cellular atlas, computer science techniques with bioinformatic methods like transcriptomic analysis and structure prediction. WLG employs computational and structural biology to predict the most pertinent receptor-ligand interactions for specific targets, be it organs or cells. For instance, in the context of improved AAV transduction, WhiteLab strives to identify membrane-associated receptors and ligands that are highly specific to a tissue as a potential target. A key differentiator regarding our approach is that we can identify biomarkers that are highly specific to a cell type in over 850 cells in the body. This enables our AI platform to design the best vector to bring the right therapeutic sequence into the cells expressing a specific phenotype.
Activities
- Service
- Research Unit
- Cardiology
- Genetic Diseases
- Oncology
- Nervous Central System
- Hematology
- Immunology
- Ophthalmology
