Contact
18 rue Alain Savary
25000 Besançon
France
Manager de l'innovation en santé
About us
PMT is a 250-member competitive cluster that federates and drives the healthcare technology sector in Burgundy-Franche-Comté through its PMT Santé Cluster, particularly in medtech and biotherapies-bioproduction, with 130 members active in healthtech. The cluster's members combine strong skills in high-level engineering (automation, AI, microfluidics, photonics, etc.), regulatory skills and the development of advanced therapy medicinal products.
Business offer
PMT Santé can put its members in touch with one another or seek out expertise for innovation projects or business development.
We organize Innovative Therapies Days, an event dedicated to feedback on the clinical trials of innovative therapies, including scientific and clinical data, regulatory affairs, production, QC, supply chain and administration. Topics covered include CAR-T cells, cell therapies (modified and unmodified) and derivatives (EV, secretome).
Activities
- Cluster / Association
- Oncology
- Hematology
- Immunology
- Inflammation
- Cell origin
- Single donor
- Pool of donors
- Cell Banking
- IPs
- MSC
- CD34 + HSC cells
- Tissue acquisition
- Apheresis
- Target cell isolation
- Differentiated Cell
- Production Cell
- Cell modification
- Direct reprogramming
- Cell Activation
- Ex Vivo & In Vivo Strategy
- Ex Vivo & In Vivo Strategy
- CMC/analytical quality assessment, quality control
- Cleaning
- Cross contamination
- Sterility
- Deviations
- Contaminants detection
- Safety for gene-edited cells
- translocation
- anti-nuclease response
- cytokine-independent growth
- Bioproduction engineering
- Cell Expansion
- Stirred tank Bioreactor
- Wave bioreactor
- Cell factory
- Microcarrier-based culture
- Organoids culture
- Capsules culture
- Scale-Up
- Process optimization
- Automated manufacturing
- On-line monitoring
- Automated high throughput microbioreactor system
- Non-GMP expansion
- GMP expansion
- Other
- Purification/Extraction
- Centrifugation
- CGMP
- Bioproduction modeling
- Metabolic / Kinetic modeling
- Formulation
- Conditioning
- Storage
- Target Identification
- Assay development in in-vitro & in-vivo models
- Research exploratory companion biomarkers
- Gene Cloning
- Gene augmentation
- KI / KO
- (Gene) engineering
- Gene Delivery System
- Lentivirus
- Adeno-Associated Virus (AAV)
- Electroporation
- Binder Generation
- Mouse immunization
- Phage Display
- Hybridoma
- CAR Construction
- Intracellular Domain
- T-cell activation/transduction
- Engineering
- Tandem CAR
- iCAR
- Ab-coupled TCR (ATCR)
- Modulation of CAR potency
- Adoptive T Cell Major Challenges in Solid Tumors
- Tumor/Ag heterogeneity
- Tumor associated Antigen
- Microenvironment
- Persistence of CAR-T
- In vivo proliferation and activation of CAR-T
- Accessibility of tumor cells
- Cell procurement
- Autologous
- Ex Vivo & In Vivo Strategy
- Ex Vivo & In Vivo Strategy
- Bioproduction/CMC/Analytical Quality Assessment, Quality Control
- Bioproduction
- Scale-Up
- Automated manufacturing
- Automated high throughput microbioreactor system
- Non-GMP pilot batch
- GMP batch
- CGMP
- Cross contamination
- Sterility
- Deviations
- Quality control
- Contaminants detection
- Safety for gene-edited cells
- Translocation
- anti-nuclease response
- cytokine-independent growth
