Oncodesign Services
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Contact
25 Avenue du Québec
91140 Villebon-sur-Yvette
France
Director - Department of Translational Pharmacology
About us
Innovative services & quality deliverables to accelerate your research program
Oncodesign Services is a contract research organization (CRO) specialized in drug discovery whose mission is to contribute to the discovery of innovative therapies against cancers and serious diseases with high medical needs.
Business offer
CRO in drug discovery and preclinical services:
- - Biophysics
- - Medicinal chemistry
- - DMPK
- - Bioanalysis and biomarkers
- - Translational pharmacology (in vitro & in vivo)
- - Pharmaco-imaging and molecular radiotherapy
Activities
- Service
- Research Unit
- Oncology
- Hematology
- Infectiology
- Immunology
- Inflammation
- Target selection & validation
- Assay development in in-vitro & in-vivo models
- Research exploratory companion biomarkers
- Hit discovery
- Screening & Identification
- In-vivo models
- In-vitro & ex-vivo models
- Immunotherapy lead generation
- Biophysical profile
- Binding & Affinity
- Functional effects
- ADCC, ADCP & CDC
- Antigen density target
- Internalization
- Pharmacology & Biological activity
- PK/PD bioavailability
- Mode of Action
- Therapeutic efficacy
- Safety
- Immunogenicity
- Hypersensitivity & allergies
- Immunotoxicology
- Specificity
- Cell activation
- Avidity testing
- Cell-based activation (APCs, AAPCs)
- Bead-base activation
- Antibody-based activation
- Ex-vivo activation (cell transfer)
- In-vivo activation (in human transgenic mouse models)
- Gene modification / Transduction
- Retroviral & lentiviral vectors
- mRNA electroporation
- CRISPR/Cas9
- Immunotherapy lead optimization
- Engineering
- ADC
- Linkers
- Payloads
- Protein scaffolds
- Fragments
- Multi-, bispecific
- Fc-fusion proteins
- Antibody humanization
- Affinity maturation
- Proof of concept
- Pharmacology potency
- Exploratory toxicology
- in-vitro & ex-vivo models
- in-vivo models
- Preclinical biomarkers
- Mechanism/Function
- Mechanism of action
- Safety
- PK/PD features
- Indication Identification
- Exploratory toxicology
- Drug-Target interaction
- Level of response duration
- Specificity
- Surrogate markers
- Research exploratory Companion biomarkers
- Animal biomarkers
- Human biomarkers
- Ex Vivo & In Vivo Strategy
- Ex Vivo & In Vivo Strategy
- Ex Vivo & In Vivo Strategy
- Ex Vivo & In Vivo Strategy
- Pathogen-host knowledge
- In-vitro and in-vivo models
- Antigen-protective immune-response profile
- Humoral response characterization:
- Antibody dosage
- Functional antibody assays (neutralization, CDC, ADCC)
- Other serological assays
- Cell mediated immunity response
- T cell assays
- Research exploratory biomarkers
- efficiency vaccination
- protection correlation
- Challenge test – Gold Standard
- In-vivo animal models
- Induced immune response characterization
- In-vitro models
- Ex-vivo models
