FEMTO-ST
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Contact
15B avenue des Montboucons
25030 BESANCON
France
Animatrice Axe Biom@x
About us
The FEMTO-ST Institute “Franche-Comté Electronics Mechanics Thermal Science and Optics – Sciences and Technologies”, is a joint research institution, which is under the quadruple authority of the Université de Franche-Comté (UFC), the Centre National de la Recherche Scientifique (CNRS), the Ecole Nationale Supérieure de Mécanique et Microtechniques (ENSMM) and the Université de Technologie Belfort-Montbéliard (UTBM).
Today, in FEMTO-ST's scientific departments and general services, we count a total staff of more than 750. The Institute is organized into seven departments :
Business offer
Biom@x is a transverse axis of FEMTO-ST aiming to ease the work of the researchers from the institute in the field of the technologies for health.
- A multi-sciences profile: 6 of the 7 departments are involved
- A strong growth: 37 funded projects in 2016, 66 projects in 2022
- Research activities from molecules, cells, organs, organisms, and up to the society
Activities
- Research Unit
- Cardiology
- Genetic Diseases
- Oncology
- Nervous Central System
- Hematology
- Infectiology
- Immunology
- Ophthalmology
- Inflammation
- Target selection & validation
- Assay development in in-vitro & in-vivo models
- Research exploratory companion biomarkers
- Hit discovery
- Screening & Identification
- In-vitro & ex-vivo models
- Immunotherapy lead generation
- Binding & Affinity
- Potency & Specificity
- Pharmacology & Biological activity
- Therapeutic efficacy
- Manufacturability
- Production quality
- Gene modification / Transduction
- Retroviral & lentiviral vectors
- mRNA electroporation
- Immunotherapy lead optimization
- Engineering
- ADC
- Linkers
- Payloads
- Protein scaffolds
- Fragments
- Multi-, bispecific
- Fc-fusion proteins
- Proof of concept
- Exploratory toxicology
- in-vitro & ex-vivo models
- Preclinical biomarkers
- Mechanism/Function
- Mechanism of action
- Exploratory toxicology
- Drug-Target interaction
- Level of response duration
- Specificity
- Bioproduction engineering
- Cell Expansion
- Stirred tank Bioreactor
- Wave bioreactor
- Cell factory
- Microcarrier-based culture
- Organoids culture
- Capsules culture
- Scale-Up
- Process optimization
- Automated manufacturing
- On-line monitoring
- Automated high throughput microbioreactor system
- Non-GMP expansion
- GMP expansion
- Other
- Purification/Extraction
- Filtration / microfiltration / ultrafiltration
- Bioproduction modeling
- Metabolic / Kinetic modeling
- Control / command
- Global optimization
- Economic analyses
- Artificial Intelligence tools
- Target Identification
- Assay development in in-vitro & in-vivo models
- Biomarker Identification
- Research exploratory Companion biomarkers
- Bioinformatics design
- Bioinformatics prediction & analysis
- Adoptive T Cell Major Challenges in Solid Tumors
- Microenvironment
- Accessibility of tumor cells
- Antigen identification, selection, optimization, and validation
- Omics analysis
- Assay development with in-vitro & in-vivo models
- Antigen selection: pathogen sequencing and functional antigens
- Surface glycoproteins
- Membrane antigens
- Pathogen-host knowledge
- Pathogen genetics and mechanism of action
- Biomolecular analysis
- In-vitro and in-vivo models
- Antigen-protective immune-response profile
- Research exploratory biomarkers
- Vaccine: antigen format platforms
- Recombinant protein expression
- Bacterial
- Cell
- Lipid delivery vehicle
- Outer-membrane vesicles (OMV)
