Deeptope
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Contact
2 rue des Adeles, Bat 440
91400 Orsay
France
Bus Dev
About us
Deeptope has developed a methodology, using a combination of technologies (Yeast Surface Display, flow cytometry and high-throughput sequencing), which makes it possible to
- replace each amino acid in a protein sequence with the 20 other amino acids,
- express all variants (each mono-mutant),
- functionally correlate the impact of each mutation on the interaction of a protein with its ligand.
We characterize protein-ligand interactions (epitope/paratope mapping) and then optimize protein sequences, generally for therapeutic indications (e.g. antibodies, cytokines, etc.).
Business offer
Generation and screening of immune libraries
Epitope mapping
Paratope mapping
Humanization
Lead optimization
Activities
- Service
- Hit discovery
- Screening & Identification
- Therapeutic libraries
- In-vitro & ex-vivo models
- Immunotherapy lead generation
- Binding & Affinity
- Potency & Specificity
- Epitope mapping
- Safety
- Specificity
- Immunotherapy lead optimization
- Engineering
- ADC
- Linkers
- Payloads
- Protein scaffolds
- Fragments
- Multi-, bispecific
- Fc-fusion proteins
- Antibody humanization
- Affinity maturation
